Role of Neurotransmitter Receptors in Mediating Light - Evoked Responses 1 in Retinal Interplexiform Cells

نویسنده

  • Wen Shen
چکیده

Role of Neurotransmitter Receptors in Mediating Light-Evoked Responses 1 in Retinal Interplexiform Cells 2 3 Zheng Jiang* and Wen Shen 4 College of Biomedical Science, Florida Atlantic University, Boca Raton, FL 33431 5 *Current address: Department of Neuroscience, Johns Hopkins University, Baltimore, MD 6 21205 7 8 Running Title: Synaptic mechanism of interplexiform cells 9 10 Pages: 32 Figures:8 Tables: 0 Words: 8302 11 12 Correspondance: 13 Dr. Wen Shen 14 College of Biomedical Science 15 Florida Atlantic University 16 BC-71, Room 229 17 777 Glades Road 18 Boca Raton, FL 33431 19 Tele: (561)-297-0628 20 Email: [email protected] 21 22

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Role of neurotransmitter receptors in mediating light-evoked responses in retinal interplexiform cells.

Interplexiform (IP) cells are a long-neglected group of retinal neurons the function of which is yet to be determined. Anatomical study indicates that IP cells are located in the inner nuclear layer, juxtaposed with the third-order neurons. However, the synaptic transmission of IP cells in the inner retina is poorly understood. Using whole cell patch-clamp and pharmacological techniques, we ext...

متن کامل

Calcium spike-mediated digital signaling increases glutamate output at the visual threshold of retinal bipolar cells.

Most retinal bipolar cells (BCs) transmit visual input from photoreceptors to ganglion cells using graded potentials, but some also generate calcium or sodium spikes. Sodium spikes are thought to increase temporal precision of light-evoked BC signaling; however, the role of calcium spikes in BCs is not fully understood. Here we studied how calcium spikes and graded responses mediate neurotransm...

متن کامل

AMPA receptor - dependent , light - evoked D - serine release acts on retinal ganglion cell NMDA 1 receptors

18 NMDA receptor (NMDAR) activation requires coincident binding of the excitatory neurotransmitter 19 glutamate and a coagonist, either glycine or D-serine. Changes in NMDAR currents during neural 20 transmission are typically attributed to glutamate release against a steady background of coagonist, 21 excluding the possibility of coagoinst release. AMPA receptor (AMPAR) stimulation evokes D-se...

متن کامل

Pii: S0042-6989(97)00296-4

Physiological and pharmacological mechanisms of glutamatergic, GABAergic and glycinergic synapses in the tiger salamander retina were studied. We used immunocytochemical and autoradiographic methods to study localizations of these neurotransmitters and their uptake transporters; and electrophysiological methods (intracellular, extracellular and whole cell patch electrode recordings) to study th...

متن کامل

Amino acid neurotransmitters in the retina: a functional overview

Physiological and pharmacological mechanisms of glutamatergic, GABAergic and glycinergic synapses in the tiger salamander retina were studied. We used immunocytochemical and autoradiographic methods to study localizations of these neurotransmitters and their uptake transporters; and electrophysiological methods (intracellular, extracellular and whole cell patch electrode recordings) to study th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009